Medical studies done on the ingredients have shown conclusively that this product is effective. 1978;49(5):269-272. Bone. Ozgur S, Sumer H, Kocoglu G. Rickets and soil strontium. 1998-2023 Mayo Foundation for Medical Education and Research. Modawal, A., Ferrer, M., Choi, H. K., and Castle, J. Strontium absorption also has effects on the absorption ofcalcium, magnesium and phosphate ions. 1 Taking magnesium oxide with food can reduce stomach troubles. Doctors arent sure exactly how it works, but it seems to help the body make more bone and keep the bone you have from breaking down. Strontium is considered to be safe in normal food amounts and as a toothpaste ingredient. AlgaeCal Plus is a plant-based calcium supplement that contains all 13 bone-supporting minerals and is clinically supported to increase bone density. Am on third brand of Strontium Citrate and doing better than on the first two. Towheed TE, Maxwell L, Anastassiades TP, et al. ", Beth Israel Deaconess Medical Center: "Strontium. Quilty PM, Kirk D, Bolger JJ, et al. View abstract. Osteoporos Int. Osteoporos.Int. Reichenbach S, Sterchi R, Scherer M, et al. (Accessed 10 October 2006). Black, D. M., Cummings, S. R., Karpf, D. B., Cauley, J. Reduce bone loss and build stronger muscles. If youre not into chemistry, then those scientific facts probably dont mean that much to you. Naess, I. View abstract. 2011;22(8):2347-2355. J.Dent.Res. Johnson, G. H., Bales, D. J., Gordon, G. E., and Powell, L. V. Clinical performance of posterior composite resin restorations. Monitoring bone strontium intake in osteoporotic females self-supplementing with strontium citrate with a novel in-vivo X-ray fluorescence based diagnostic tool. Results of Russian multicenter trial]. 2010;46(4):1038-1042. doi: 10.1016/j.bone.2009.12.006. Reginster, J., Minne, H. W., Sorensen, O. H., Hooper, M., Roux, C., Brandi, M. L., Lund, B., Ethgen, D., Pack, S., Roumagnac, I., and Eastell, R. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. 2003;14 Suppl 3:S56-S65. Performance Lab Flex - Best For Athletes. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. 2004;5(7):1635-1638. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. View abstract. 2012;23(1):295-303. doi: 10.1007/s00198-011-1547-8. 2002;13(12):925-931. Strontium, which is a trace element found in seawater and soil, has a chemical similarity to calcium and can replace calcium in the bone. As a service to our readers, American Bone Health provides access to our library of archived content. Do not be misled by marketing materials that compare them to strontium ranelate. This supplement supports healthy osteoblast differentiation osteoblast collagen formation and balanced osteoclast activity; all of these activities help you maintain bone tensile strength. 2007;19(4):330-333. Strontium ranelate acts through dual mechanisms of inhibiting resorption by osteoclasts and maintaining or stimulating bone formation by osteoblasts. Any feedback to help me through this maze will be highly appreciated. Available at: https://www.fda.gov/cder/ogd/approvals/1stgen0103.htm. 2005 - 2023 WebMD LLC. I'm glad you found us. View abstract. 2011;(7):CD003347. Baziotis N, Yakoumakis E, Zissimopoulos A, et al. However, supplementation with strontium has not yet been studied as tooth decay prevention. I was diagnosed with osteopenia a little over a year ago but have not done anything other than trying to add more calcium rich food to my diet. Cancer that has spread to bone and causes pain. View abstract. (Strontium may remain in the bones for as long as 710 years after the last dose.) If you are concerned about the bone-thinning disease osteoporosis, you may have heard about treatment with strontium. Arthritis Rheum. Thromb.Haemost. It can be found in soil and seawater, and its actually used as a supplemental treatment for osteoporosis and other bone diseases. 2005;16(10):1291-1298. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. View abstract. Calcium is important for bone health throughout your life. J Am Diet Assoc 1987;87:1644-50. 2005 - 2023 WebMD LLC. View abstract. Doctors can prescribe it only for postmenopausal women and for men with severe osteoporosis who cant take other drugs. J Clin.Dent. Bruyere, O., Burlet, N., Delmas, P. D., Rizzoli, R., Cooper, C., and Reginster, J. Y. Marquis, P., Roux, C., de la Loge, C., Diaz-Curiel, M., Cormier, C., Isaia, G., Badurski, J., Wark, J., and Meunier, P. J. Strontium ranelate prevents quality of life impairment in post-menopausal women with established vertebral osteoporosis. View abstract. Overall, the results of this 2013 study performed with male subjects demonstrated that strontium ranelate supplementation appears to improve bone mineral density in men similar to the way it has been shown to help postmenopausal women struggling with osteoporosis. After you stop taking any of these bone-building medications, you generally will need to take another osteoporosis drug to maintain the new bone growth. Rizzoli R, Chapurlat RD, Laroche JM, et al. Osteoporosis: Prevention With Calcium Treatment - Cleveland Clinic Metastron prescribing information. The effect of a strontiumhloridetoothpaste on root hypersensitivity in a controlled clinical study. Pearce, E. I. and Sissons, C. H. The concomitant deposition of strontium and fluoride in dental plaque. View abstract. This is more important for postmenopausal women. It is given as an injection every month at your doctor's office and is limited to one year of treatment. Sr should be used with caution for those with kidney disease and if you have advanced kidney disease, then strontium ranelate is not recommended at all. (21). J Bone Miner Res 2008;23(S80). Black, D. M., Delmas, P. D., Eastell, R., Reid, I. R., Boonen, S., Cauley, J. 2008;80(5):47-52. Rheumatol.Int. What you need to know about strontium suppements for osteoporosis. View abstract. Antacids are used to decrease stomach acid. Use strontium supplements with caution if you have kidney disease. Wang, C. T., Lin, J., Chang, C. J., Lin, Y. T., and Hou, S. M. Therapeutic effects of hyaluronic acid on osteoarthritis of the knee. A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss when used in postmenopausal women with osteoporosis. The effect of prior bisphosphonate therapy on the subsequent therapeutic effects of strontium ranelate over 2 years. Dent.Clin.North Am. Hahn, G. S. Strontium is a potent and selective inhibitor of sensory irritation. View abstract. 23(1):305-315. doi: 10.1007/s00198-011-1758-z. https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869. [RETRACTED]. Even though its not considered a nutrient, its known that the human body can absorb strontium and utilize it as it would calcium. 2000;11(1):83-91. We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available strontium citrate reviews currently available on the market. 1987;66(10):1518-1522. Osteoporosis Int. I found that Strontium is eliminated by the kidneys and can build up in people with poor kidney function. 1967;5(6):318-321. View abstract. Connect with thousands of patients and caregivers for support and answers. Proc.R.Soc.Lond B Biol.Sci. View abstract. Osteoporos.Int. Spector, T. D., Conaghan, P. G., Buckland-Wright, J. C., Garnero, P., Cline, G. A., Beary, J. F., Valent, D. J., and Meyer, J. M. Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]. Although many people have never heard of it before, its a very interesting and somewhat controversial supplement. 2006;45(3):179-185. J.Am.Dent.Assoc. View abstract. Magnesium Oxide: Benefits, Dosage, and Side Effects - Verywell Health However, I dont advocate using these supplements without first reviewing the precautions listed below and talking with your health care provider. J.Dent. For two years, 174 of the men received 2 grams of strontium ranelate per day while 87 men received a placebo. A., Hoiseth, A., Felsenberg, D., Huss, H., Gilbride, J., Schimmer, R. C., and Delmas, P. D. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. (. View abstract. Seafood is a top source of Sr, but it can also be found in smaller quantities in whole milk, grains,beans, spinach, lettuce, celery, androot vegetableslike carrots and potatoes. Here with us today, we have two experts. Glucosamine therapy for treating osteoarthritis. Do not take it within 2 hours of ingesting calcium so I take it at bedtime. Meunier PJ, Slosman DO, Delmas PD, et al. 1992;19(10):737-740. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. How can Sr be used? Get answers to some of the most common questions about osteoporosis treatment. 2004;19(8):1241-1249. Dahl SG, Allain P, Marie PJ, et al. View abstract. Dr. Lanis No-Nonsense Bone Health Guide. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. It boils at 2,520 degrees F (1,382 degrees C) and melts at1,431 degrees F (777 degrees C). 2006;34(8):608-613. Uchida, A., Wakano, Y., Fukuyama, O., Miki, T., Iwayama, Y., and Okada, H. Controlled clinical evaluation of a 10% strontium chloride dentifrice in treatment of dentin hypersensitivity following periodontal surgery. Before you consider calcium supplements, be sure you understand how much calcium you need, the pros and cons of calcium supplements, and which type of supplement to choose. Scand J Rheumatol 2001;30(4):242-247. Clin Chem 2000;46:248-51. 2014 Apr;61:48-54. doi: 10.1016/j.bone.2014.01.002. [2] Royal Osteoporosis Society. Quintessence.Int. Most calcium supplements are big and difficult to swallow. View abstract. Fidelix, T. S., Soares, B. G., and Trevisani, V. F. Diacerein for osteoarthritis. Strontium ranelate is available as a prescription medication in Europe and Australia, but it has not been approved by the FDA in the United Sates. Kanapka, J. A number of studies have shown that it can strengthen bone and reduce the risk of fractures, even among women 74 years of age or older when risks are highest. Biol.Trace Elem.Res. Overall, the review concludes: For patients with castration-resistant prostate cancer suffering from malignant bone pain, treatment with a bone-seeking radiopharmaceutical is a relevant therapeutic option often resulting in significant pain reduction. (4a) In addition, strontianite is a mineral that comes from concentrations of strontium compounds, and there are several strontium compounds. The product can increase bone density, and it can also slow down bone loss. Interested in more discussions like this? Ashayeri E, Omogbehin A, Sridhar R, Shankar RA. 2012. Sr can be found in Group 2 of the periodic table. View abstract. Calcium, Bone Density and Osteoporosis with Drs. Pelin Batur and Chad 2-1-2001;344(5):333-340. A prescription form of strontiumstrontium ranelate (the ranelate salt), known as Protelos/Osseor was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip. When people are looking into options for osteoporosis medications, some people want to take the natural route and choose to make strontium a part of their treatment plan. Strontium ranelate is comprised of 27.8% strontium and 72.2% ranelic acid. 2007;357:nihpa40967. Our team aims to be not only thorough with its research, but also objective and unbiased. Acta Derm Venereol. I am actively and urgently in the process of deciding which osteoporosis treatment I want to "pitch" to my doctors. This article will be helpful to you if you experience joint discomfort, especially from rheumatoid arthritis and other joint health disorders. View abstract. Calcium citrate is another of the more common calcium types used in calcium supplements. 2013 Sep 4;93(5):520-6. doi: 10.2340/00015555-1564. (Accessed 13 March 2004). J.Thromb.Haemost. Hernandez, F., Mohammed, C., Shannon, I., Volpe, A., and King, W. Clinical study evaluating the desensitizing effect and duration of two commercially available dentifrices. Doggrell, S. A. Strontium is a trace mineral that may aid bone health by reducing bone loss and encouraging bone development. Zinc: Benefits, intake, sources, deficiency, and side effects [4] Simpson, Lani. Theres not enough research to know if strontium fights osteoporosis. 7-27-1965;162(989):458-472. About 99% of the strontium in the human body is concentrated in the bones. No difference in intestinal strontium absorption after an oral or an intravenous 1,25(OH)2D3 bolus in normal subjects. Osteoporosis Int. Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis. Minkoff S, Axelrod S. Efficacy of strontium chloride in dental hypersensitivity. Cummings SR, McClung MR Christiansen C et al. [No authors listed]. Eur Urol 2003;44:519-26. Blake, G. M., Zivanovic, M. A., McEwan, A. J., and Ackery, D. M. Sr-89 therapy: strontium kinetics in disseminated carcinoma of the prostate. Its been compared to calcium in its bone-boosting abilities. A double-blind, randomized placebo-controlled trial published in The Journal of Clinical Endocrinology and Metabolism looked at the effects of Sr on 261 men with primary osteoporosis. Mason, S., Hughes, N., Sufi, F., Bannon, L., Maggio, B., North, M., and Holt, J. J Bone Miner Res 2001;16:299-308. . 5 Reasons to Add Lamb Meat to Your Diet. Cochrane.Database.Syst.Rev. A 2016 systematic review published in European Urology took a look at several radiopharmaceuticals including Sr-89 for reducing the malignant bone pain from prostate cancer. Reginster, J. Y., Deroisy, R., Dougados, M., Jupsin, I., Colette, J., and Roux, C. Prevention of early postmenopausal bone loss by strontium ranelate: the randomized, two-year, double-masked, dose-ranging, placebo-controlled PREVOS trial. Pure Encapsulations Strontium (citrate) - 180 Capsules - PureFormulas N.Engl.J.Med. View abstract. Addy, M., Mostafa, P., and Newcombe, R. G. Effect of plaque of five toothpastes used in the treatment of dentin hypersensitivity. 2006;54(10):3205-3211. Bianchi ML, Ardissino GL, Schmitt CP, et al. Strontium is a mineral found in seawater and soil. (7,8), There have been more studies that show the positive effects of strontium ranelate on osteoporosis and bone fractures. Boron: Benefits, Side Effects, Dosage, and Interactions - Verywell Health It seems to play a role in how your body makes new bone while it slows the breakdown of old bone. (14). Benefit: Bone & Joint Health. Clin Sci 1968;34:351-63. J Clin Endocrinol Metab 2002;87:2060-6.. View abstract. Phone & Address: 1-800-820-0184; [email protected]. Strontium Boost is an all-natural organic supplement that supports bone health in people of every age. I did find some information on the Mayo Clinic website on osteoporosis. 11 possible benefits. Collins, J. F. and Perkins, L. Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity. View abstract. Upset stomach and diarrhea are the most common side effects of magnesium oxide. Caution with Kelp Supplements: May Contain Too Much Iodine Fluoride helps protect your teeth from the acid that is released when this happens. 2008;9:165. Chemical exchange between glass-ionomer restorations and residual carious dentine in permanent molars: an in vivo study. Esomeprazole (Nexium) is not the same medication as esomeprazole strontium, although both are used to treat similar stomach conditions. However, Sr-89 (a radioactive form) is considered to be unsafe for pregnant and breast-feeding women. There were, however, significant increases in both heart attacks and blood clots (including pulmonary embolism) in patients taking strontium ranelate compared to those who were not. J.Clin.Periodontol. Oncology 1998;55:377-81. They won't do any studies but the END OF FRACTURES SAYS IT ALL! View abstract. My teeth are really strong and it feels like my bones are too. View abstract. 2008;19(4):503-510. To avoid this interaction, take strontium at least 2 hours before or after taking quinolones. Bellamy, N., Campbell, J., Robinson, V., Gee, T., Bourne, R., and Wells, G. Viscosupplementation for the treatment of osteoarthritis of the knee. Estrogens might decrease how fast the body gets rid of strontium. Chesnut, C. H., III, Silverman, S., Andriano, K., Genant, H., Gimona, A., Harris, S., Kiel, D., LeBoff, M., Maricic, M., Miller, P., Moniz, C., Peacock, M., Richardson, P., Watts, N., and Baylink, D. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. Physio Flex Pro - Editor's Choice. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. Strontium Citrate Demonstrates its Safety and Effectiveness Many consumers are being lured by the advertised benefits of strontium for bone health. J.Clin.Endocrinol.Metab 2005;90(5):2816-2822. Zinner, D. D., Duany, L. F., and Lutz, H. J. (23), In general, taking very high doses of a Sr supplement is typically not considered safe and taking too much could even damage bones, so be careful when taking strontium, as recommended by the ATSDR (Agency for Toxic Substances and Disease Registry). Moise H, Chettle DR, Pejovic-Milic A. View abstract. Sr-89 has been used as a form of treatment to manage pain resulting from bone pain due to cancer. Some quinolone antibiotics include ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin, moxifloxacin (Avelox), and others. View abstract. (10), Radioactive strontium-89 is given intravenously for advanced bone cancer or cancer that has spread to the bones such as metastatic prostrate cancer. (24, 25). Description Pure Encapsulations' Strontium capsules provide one of the many trace minerals essential to bone health. Blitzer, B. View abstract. Strontium Ranelate returns to the UK as an osteoporosis drug treatment. 2019, As a service to our readers, American Bone Health provides access to our library of archived content. Zinc is crucial for various functions in the body, including: 1. It is an alkaline earth metalmost similar to barium and calcium. A meta-analysis of randomized controlled trials. 5-10-2001;344(19):1434-1441. PROOF Study Group. View abstract. Over-the-counter dentifrices in the treatment of tooth hypersensitivity. A., Thompson, D. E., Nevitt, M. C., Bauer, D. C., Genant, H. K., Haskell, W. L., Marcus, R., Ott, S. M., Torner, J. C., Quandt, S. A., Reiss, T. F., and Ensrud, K. E. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. View abstract. 1978;57(9-10):903. Most people who take strontium citrate report their fractures STOP. Research from Europe suggests that patients on strontium ranelate may have an increased risk of heart attacks. Omdahl JL, DeLuca HF. View abstract. 2009;20(10):1663-1673. Erythritol: Is This Healthy Sweetener the Real Deal? The body needs zinc for the immune system to work properly. are clickable links to these studies. Ann.Rheum.Dis. Toxicity is minimal and consists of a transient 30 percent reduction of the [platelet] count. You are lucky to still be able to get some control over this. 2009;41(7):559-562. J Clin Endocrinol Metab 1966;26:566-72. Dermatology 2000;200(3):244-246. 2006;55(8):669-675. View abstract. 2010;21(12):1993-2002. It can be found in soil and seawater as well as some foods. Papoiu AD, Valdes-Rodriguez R, Nattkemper LA, Chan YH, Hahn GS, Yosipovitch G. A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch. Efficacy and safety of strontium ranelate in the treatment of osteoporosis in men. Lo, G. H., LaValley, M., McAlindon, T., and Felson, D. T. Intra-articular hyaluronic acid in treatment of knee osteoarthritis: a meta-analysis. Research shows that a special prescription form of strontium (strontium-89 chloride) given intravenously (by IV) reduces pain from metastatic, Weak and brittle bones (osteoporosis). View abstract. Health Phys 2004;86:193-6. Maheu E, Mazieres B, Valat JP, et al. Rozhinskaia, L. I., Arapova, S. D., Dzeranova, L. K., Molitvoslovova, N. N., Marova, E. I., Il'in, A. V., Benevolenskaia, L. I., Nikitinskaia, O. This technology we use to assemble our list depends on a variety of factors, including but not limited to the following: Brand Value: Every brand of strontium citrate . It was recommended to my sister by her doctor. 1990;34(3):545-560. View abstract. Obtaining strontium from your diet by eating seafood, whole grains,beans, spinach, lettuce, celery, androot vegetableslike carrots and potatoes is the safest way to boost your strontium levels. View abstract. Results of a 2-year study. @faith123, recently posted about having a second reclast infusion recently here, https://connect.mayoclinic.org/discussion/reclast-infusion/. View abstract. Types of Calcium Used in Food Supplements - AlgaeCal Strontium is similar to calcium. AlgaeCal Strontium Boost Reviews - CSUPERB Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect.